Search

Antiviral and Antibacterial Properties of Sasanqua Saponin

Sasanqua Saponin is glycoside compound extracted from Camellia Seeds. The Camellia plant yields different types of tea based on the oxidation process (Black or Green). The Saponin is extracted from using water extraction techniques. The common technique is the Vanillin - Sulphuric Acid Method, "The colorimetric assay used for Saponin quantification in plant extracts is subject to interference by common solvents used to extract Saponin from plant materials. Therefore, the degree of interference of ten common solvents was investigated. It was found that the. presence. of acetone, methanol and n-butanol in the reaction. solution caused an intense darkening of the reaction solution in the absence of Saponin, which likely could lead to erroneous Saponin content values. Using aescin to construct standard curves with different solvents such as water".


What Can Saponin Do?

Saponin occurs naturally as plants glycoside that have many useful pharmacological properties and it proven to be anti-tumorigenic, antiviral, antidiabetic, antiobesity, and gastroprotective. There have. been studies. to determine the usefulness of Saponin against. some of the viruses. "When ingested by humans, Saponin also seems to help our immune system and to protect against viruses and bacteria. Studies with ovariectomized-induced rats have shown that some Saponin, such as the steroidal Saponin from Anemarrhena asphodeloides, a Chinese herb, have a protective role on bone loss".


Hepatitis C Virus

The importance of Saponin became clear in the study to determine if Saponin have any properties as an anti-hepatitis C activity. Hepatitis C virus (HCV) is a major cause for chronic liver disease leading to liver cirrhosis and hepatocellular carcinoma (HCC). The study shows that "HCV replication was efficiently inhibited at a concentration of 10 mg/ml of Saponin in cell culture grown HCV (HCVcc)-infected cells. Inhibitory effect of Saponin on HCV replication was verified by quantitative real-time PCR, reporter assay, and immunoblot analysis. In addition, Saponin potentiatedIFN-a-induced antiHCV activity. Moreover, Saponin exerted antiviral activity even in IFN-a resistant mutant HCVcc-infected cell". The study's evidence suggests that Saponin may have the potential as a therapeutic agent for HCV patients.



1 view0 comments

© 2020 Etalink US Incorporated

Site by